Teflon® PFA, FEP, and PTFE for Pharmaceutical Applications

DuPont offers a full range of Teflon® PFA, FEP, and PTFE for manufacturing components used in pharmaceutical processes. They provide a high level of cleanability and durability, along with low operating maintenance costs.

Quality and flexibility are crucial for today's pharmaceutical and biopharmaceutical manufacturing facilities, which must produce a range of products while maintaining product integrity and purity. To maintain high quality standards, the pharmaceutical industry is turning to DuPont fluoropolymers for piping, components, and vessels that are superior to traditional stainless steel and glass.


Teflon® PFA and Teflon® PTFE for Pharmaceutical Applications

With their excellent chemical and thermal resistance, Teflon® PFA, Teflon® FEP, Tefzel® ETFE, and Teflon® PTFE are ideal for pharmaceutical and biopharmaceutical processing equipment. Their molecules, which have continuous non-reactive surfaces, are compatible with virtually all chemicals and solvents. And because articles processed from Teflon® PFA, FEP, and PTFE are non-reactive, there are no corrosion byproducts or extractables to contaminate processes.

Teflon® fluoropolymers resist absorption of chemicals. In addition to their higher service temperatures, they are more resistant to chemical attack than conventional chlorinated and hydrocarbon polymers.


Superior Cleanability

Teflon® finishes are easy to clean. They provide smooth, non-wetting, hydrophobic surfaces that resist biofilm buildup, and can be used with the strongest cleaning solutions and steam-in-place processes. Also, since they resist buildup of process materials, intervals between cleanings can often be extended.

From heat-shrink FEP and PTFE tubing to ultra-lite PTFE liners with walls as thin as 0.0005", we offer extrusions with outstanding tolerance control, length accuracy, and tubing consistency.

To meet some of the most demanding requirements, here are some uses of Teflon® PFA, Teflon® FEP, Tefzel® ETFE, and Teflon® PTFE for pharmaceutical and biotechnology processes:

  • Pipe linings, fittings and valves.
  • Tubing and fittings for fluid transfer.
  • Single- and multi-lumen tubes.
  • Braid or coil reinforced hose.
  • Bulk vessel linings.
  • Heat-shrink and spiral heat-shrink.


The Material of Choice for PFA-Lined, Large-Diameter

Pipe Fittings

With nearly universal chemical resistance and a smooth surface for excellent cleanability, DuPont™ Teflon® PFA fluoropolymer resin has become an ideal lining in large-diameter pipe fittings for the pharmaceutical industry.

In multi-purpose pharmaceutical plants, process pipework is often required to convey different materials. The exceptionally smooth surface and low wettability of Teflon® PFA assists both cleaning and changeover. The cleanliness of PFA is also a key attribute, particularly during high-purity sulphuric and hydrofluoric acid production. 

Teflon® PFA is a reliable, consistent material for large pipe fittings, having great thermal stability, resistance to stress cracking, and a generally very forgiving character in use. 

The superior permeation performance of Teflon® PFA protects against liner collapse due to permeation and inadequate venting, which can lead to significant plant failures and extended shutdowns.

Among the unique features of Teflon® PFA is the development of the 90-degree elbow. To offer this, DuPont has extended its range of investment in steel castings, creating a one-piece (versus a more usual three-piece) design. 

Teflon® PFA, FEP, and PTFE for pharmaceutical applications offer the superior purity, quality, and cleanliness that pharmaceutical operations demand.

The information provided on this website is for reference only. Always refer to the product labels for complete details and directions for use.