Hexafluoroisopropanol (HFIP) is a water-white liquid available in two grades to meet your needs. HFIP technical is a high purity grade suitable for most chemical formulating. HFIP Specialty Solvent is especially designed for laboratory solvent applications. HFIP is highly polar, miscible with water and many organic solvents, thermally stable, and transparent to UV light. These properties make it ideal as a solvent in many polymer systems. Additional information on uses is given below.
Sales Specifications
Hexafluoroisopropanol Technical
| Property | Limit |
| Purity, % | 99.0 min. |
| Water, % | 0.1 max. |
| Pentafluoroisopropanol, ppm | 1000 max. |
| Hexafluoropropane, ppm | 1000 max. |
| Hexafluoropropene, ppm | 1000 max. |
| Trifluoroethanol, ppm | 1000 max. |
| Trifluoropropanol, ppm | 1000 max. |
| Hexafluoroisopropyl perfluoropropionate, ppm | 2000 max. |
| Other impurities, ppm | 3000 max. |
|
Hexafluoroisopropanol Specialty Solvent
| Property | Limit |
| Purity, % | 99.97 min. |
| Water, ppm | 100 max. |
| Pentafluoroisopropanol, ppm | 50 max. |
| Hexafluoroacetone, ppm | 40 max. |
|
Uses
HFIP is a used as an intermediate for pharmaceuticals and agrochemicals, and as a solvent or cleaner in electronics. In addition, HFIP finds use in analytical applications due to its ability to dissolve a variety of polymers including polyesters, polyamides, polyacrylonitriles, polyacetals, and hydrolyzed polyvinyl esters.
HFIP is a volatile and polar material, with high density, low viscosity and low surface tension. It is transparent to UV light (<2000 A), and has a low refractive index.
Solvent Properties
Hexafluoroisopropanol exhibits strong hydrogen bonding and will associate with and dissolve most molecules with receptive sites such as oxygen, double bonds, or amine groups. Stable distillable complexes are formed with many ethers and amines due to strong hydrogen bonding. HFIP is soluble in water and most organic solvents, but immiscible with long chain alkanes.
Typical Physical Properties*
| Property | Value |
| CAS Name | 1,1,1,3,3,3-Hexafluoro-2-propanol |
| CAS Number | 920-66-1 |
| Formula | C4H4F6O |
| Molecular weight | 168.05 |
| Form | Water-white liquid |
| Boiling Point | 58.2 C (136.8 F) |
| Melting Point | -3.3 C (26 F) |
| Density, 25 C (77 F) | 1.6047 g/ml |
| Refractive index, nd25 | 1.2752 |
| Surface tension, 25 C (77 F) | 16.14 dyn/cm |
Viscosity at 25 C (77 F)
at 38 C (100 F) | 1.021 cs
0.670 cs |
| Coefficient of expansion | 0.0018/deg C (0.0010/deg F) |
| Latent heat of vaporization | 52 cal/g (93 Btu/lb) |
| Vapor pressure | 120 mm Hg at 20 C (68 F) |
| *This table gives typical properties based on historical production performance. DuPont does not make any express or implied warranty that these products will continue to have these typical properties. |
|
Handling
HFIP is corrosive to eyes on contact, and a strong skin and respiratory irritant. Care should be taken to avoid contact by wearing appropriate gloves, safety glasses and other protective equipment as needed. Refer to the MSDS for further handling information. This product may also contain a very low level of hexafluoroacetone, which is a potential reproductive hazard.
Recovering Product
Users may find it cost effective to recover HFIP by distillation in order to reuse it. For further information, refer to Perrin, et al "Purification of laboratory chemicals," Pergamon Press, 1980.
Packages
HFIP Technical is supplied in bulk isotanks, and in 160 kg (352.7 lb) net drums. HFIP Specialty Solvent grade is available in 5.44 kg (12 lb) pails. Samples of 401 g (250 mL) are also available.
| 
