Reduce Transmission of Citrus Greening Disease

Huanglongbing, or greening disease, is known as the most devastating citrus disease in the world.

The Asian citrus psyllid (ACP), Diaphorina citri Kuwayama, is an invasive citrus pest in the U.S. It vectors the bacteria Candidatus Liberibacter asiaticus, which causes huanglongbing  (HLB) or citrus greening, known as the most devastating disease of citrus in the world. Citrus greening was first detected in Florida citrus in August 2005; since then, it has appeared in Texas (January 2012) and California (March 2012).

  • Managing populations of ACP with insect control products is a recommended practice for reducing the impact of greening on citrus production.
  • DuPont Exirel® insect control powered by Cyazypyr® was granted reduced-risk classification by the EPA for all registered crops and is selective for beneficial arthropods, except bees.
  • Exirel® has been assigned to IRAC group 28 (ryanodine receptor modulators). It delivers a novel mode of action for psyllids and other sucking pests, with no cross-resistance to existing chemistries.
  • Exirel® impacts insects by impairing muscle function. Intoxicated insects stop feeding rapidly, resulting in excellent plant protection and the reduction of some insect-vectored diseases.

Reduce Transmission of Greening Disease by Asian Citrus Psyllid

In laboratory studies conducted by private researchers, the USDA and IFAS University of Florida, researchers found that Exirel® can reduce the ability of ACP adults to transmit greening disease in multiple ways:

  • Rapid feeding cessation, which prevents psyllids from acquiring and or transmitting the bacteria when they feed in the plant’s phloem
  • Lack of preference of adult ACP settling on Exirel®-treated plants
  • Direct control of ACP adults and nymphs, which prevents feeding and secondary spread of the disease

Read the study details and results here.

Exirel® Benefits in Citrus


  • Protection of new flush
  • Protection from greening disease
  • Yield improvement from grower standard program
  • Better fruit quality (fewer markings on fresh)


  • Nondisruptive to beneficials, except bees
  • Nonpersistent in the environment and negligible toxicity to mammals, birds, fish and earthworms*
  • New mode of action (MOA) for sucking insects


  • Granted reduced-risk classification from EPA under its Reduced Risk Pesticide Program for all registered crops
  • Minimal PPE requirements

*A buffer zone of 25 feet is required to mitigate toxicity to some aquatic and sediment invertebrates.


The EPA registered label for Exirel® contains the statement, “This product is highly toxic to bees exposed to direct treatment on blooming crops or weeds. Do not apply this product or allow to drift to blooming crops or weeds if bees are foraging in the treatment area.” 


The information provided on this website is for reference only. Always refer to the product labels for complete details and directions for use.